BBQ Bob's is a restaurant that Jesse Travis and Steve Sloan co-own starting in the sixth season. Mark Sloan is also a silent partner. It is located in a small strip mall very close to Community General Hospital.

Other stores around it include a jewelery store, travel agency and a bank. It is often frequented by the hospital staff as an alternative to the hospital cafe. All staff members get discounts. The exterior of BBQ Bob's was based on a storefront at the Whizin's Center in Agoura, California, where exterior scenes of BBQ Bobs were occasionally filmed.